Tuesday, November 5, 2024

Spanish scientific discovery: age not only weakens the immune system, but also leads to infection with the herpes virus

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https://mundo.sputniknews.com/20211124/hallazgo-cientifico-espanol-no-solo-la-edad-desgasta-al-sistema-inmunitario-tambien-un-herpesvirus-1118589130.html

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https://mundo.sputniknews.com/20210829/estos-son-los-peores-habitos-alimentarios-para-tu-sistema-inmunitario-1115508375.html

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💗 health, cordoba, virus, research, immune system

Researchers from the University of Cordoba discovered that the herpes virus “cytomegalovirus” contributes to the chronic deterioration of the human body’s defenses. The viral origin of this vulnerability means opening the perspective of being able to stop it, rather than being linked exclusively to age.

A research team from the University of Córdoba (UCO), together with Maimonides Institute for Biomedical Research in Córdoba (Imibic) and the University of Tübingen (Germany), determined that the herpes virus Cytomegalovirus (CMV) is able to accelerate the erosion of the immune system regardless of age. In other words, there is no only chronological factor.

Led by physicians Rafael Solana and Alejandra Pera, and supported by researcher Fakhri Hassouna, the group has been studying for years whether Wear and tear and changes in the immune system They were a product of age or if CMV was also involved. To this end, they distributed 119 people into three age groups (young, middle-aged and old), who were in turn divided into two further groups: those who had CMV infection and those who did not. They analyzed the modifications he had undergone T lymphocytes either way. The sample included a group of healthy German individuals.

It has been observed that infection with the herpes virus in some people caused the expansion of inflammatory cells and affects atherosclerosis, with the ability to cause various vascular disorders, and even increase the chances of suffering by 20%. Cardiovascular disease. “Not all people who contract the virus generate these types of cells, but those who do contract them, build up and when they cross a threshold, they can cause serious problems,” Dr. Bera said in a press release provided by UCO. .

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T lymphocytes, the key

The T lymphocytes responsible for assembling defense against viruses or cellular changes produced by cancer are T lymphocytes, and when encountered, these lymphocytes generate a memory by which they recognize the aggressor in subsequent infections. The result is that the reaction time is shorter.

Cytomegalovirus (CMV) is a very common type of herpes virus, which can spread in their bodies with age, reactivating from time to time. Although CMV does not produce any type of symptoms, it does cause inflammation strong effect In the immune system, where it must constantly control it by creating a memory, which corrodes it often. for operation weak immune system With age it is called immunity. Researcher Alejandra Pera concludes, “The advantage of knowing that all of this may have a viral origin is that we can stop it. If it’s exclusively age-related, we can’t stop it.”
The research group is also studying the behavior of these cells in heart patients to determine the risk threshold. Also, the incidence of cytomegalovirus in the immune system Combined with COVID-19. All research is funded by the Carlos III Health Institute, the Ministry of Health and the German Academic Exchange Service (DAAD), as well as other regional bodies.

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